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Sacral nerve stimulation for faecal incontinence alters colorectal transport.

Identifieur interne : 002164 ( Main/Exploration ); précédent : 002163; suivant : 002165

Sacral nerve stimulation for faecal incontinence alters colorectal transport.

Auteurs : RBID : pubmed:18412293

English descriptors

Abstract

Sacral nerve stimulation reduces the frequency of defaecation in patients with faecal incontinence. The aim of this study was to examine the mechanism behind the reduced number of bowel movements in incontinent patients treated with sacral nerve stimulation.

DOI: 10.1002/bjs.6083
PubMed: 18412293

Links toward previous steps (curation, corpus...)


Le document en format XML

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<title xml:lang="en">Sacral nerve stimulation for faecal incontinence alters colorectal transport.</title>
<author>
<name sortKey="Michelsen, H B" uniqKey="Michelsen H">H B Michelsen</name>
<affiliation wicri:level="1">
<nlm:affiliation>Surgical Research Unit, Department of Surgery P, Aarhus University Hospital, Aarhus, Denmark. hbn@mail.tele.dk</nlm:affiliation>
<country xml:lang="fr">Danemark</country>
<wicri:regionArea>Surgical Research Unit, Department of Surgery P, Aarhus University Hospital, Aarhus</wicri:regionArea>
</affiliation>
</author>
<author>
<name sortKey="Christensen, P" uniqKey="Christensen P">P Christensen</name>
</author>
<author>
<name sortKey="Krogh, K" uniqKey="Krogh K">K Krogh</name>
</author>
<author>
<name sortKey="Rosenkilde, M" uniqKey="Rosenkilde M">M Rosenkilde</name>
</author>
<author>
<name sortKey="Buntzen, S" uniqKey="Buntzen S">S Buntzen</name>
</author>
<author>
<name sortKey="Theil, J" uniqKey="Theil J">J Theil</name>
</author>
<author>
<name sortKey="Laurberg, S" uniqKey="Laurberg S">S Laurberg</name>
</author>
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<date when="2008">2008</date>
<idno type="doi">10.1002/bjs.6083</idno>
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<keywords scheme="KwdEn" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Defecation (physiology)</term>
<term>Electric Stimulation Therapy (methods)</term>
<term>Fecal Incontinence (physiopathology)</term>
<term>Fecal Incontinence (radionuclide imaging)</term>
<term>Fecal Incontinence (surgery)</term>
<term>Female</term>
<term>Gastrointestinal Transit (physiology)</term>
<term>Humans</term>
<term>Indium Radioisotopes (diagnostic use)</term>
<term>Male</term>
<term>Middle Aged</term>
<term>Sacrum (innervation)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en">
<term>Indium Radioisotopes</term>
</keywords>
<keywords scheme="MESH" qualifier="innervation" xml:lang="en">
<term>Sacrum</term>
</keywords>
<keywords scheme="MESH" qualifier="methods" xml:lang="en">
<term>Electric Stimulation Therapy</term>
</keywords>
<keywords scheme="MESH" qualifier="physiology" xml:lang="en">
<term>Defecation</term>
<term>Gastrointestinal Transit</term>
</keywords>
<keywords scheme="MESH" qualifier="physiopathology" xml:lang="en">
<term>Fecal Incontinence</term>
</keywords>
<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en">
<term>Fecal Incontinence</term>
</keywords>
<keywords scheme="MESH" qualifier="surgery" xml:lang="en">
<term>Fecal Incontinence</term>
</keywords>
<keywords scheme="MESH" xml:lang="en">
<term>Adult</term>
<term>Aged</term>
<term>Female</term>
<term>Humans</term>
<term>Male</term>
<term>Middle Aged</term>
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<front>
<div type="abstract" xml:lang="en">Sacral nerve stimulation reduces the frequency of defaecation in patients with faecal incontinence. The aim of this study was to examine the mechanism behind the reduced number of bowel movements in incontinent patients treated with sacral nerve stimulation.</div>
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<PMID Version="1">18412293</PMID>
<DateCreated>
<Year>2008</Year>
<Month>05</Month>
<Day>05</Day>
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<DateCompleted>
<Year>2008</Year>
<Month>05</Month>
<Day>27</Day>
</DateCompleted>
<Article PubModel="Print">
<Journal>
<ISSN IssnType="Electronic">1365-2168</ISSN>
<JournalIssue CitedMedium="Internet">
<Volume>95</Volume>
<Issue>6</Issue>
<PubDate>
<Year>2008</Year>
<Month>Jun</Month>
</PubDate>
</JournalIssue>
<Title>The British journal of surgery</Title>
<ISOAbbreviation>Br J Surg</ISOAbbreviation>
</Journal>
<ArticleTitle>Sacral nerve stimulation for faecal incontinence alters colorectal transport.</ArticleTitle>
<Pagination>
<MedlinePgn>779-84</MedlinePgn>
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<ELocationID EIdType="doi" ValidYN="Y">10.1002/bjs.6083</ELocationID>
<Abstract>
<AbstractText Label="BACKGROUND" NlmCategory="BACKGROUND">Sacral nerve stimulation reduces the frequency of defaecation in patients with faecal incontinence. The aim of this study was to examine the mechanism behind the reduced number of bowel movements in incontinent patients treated with sacral nerve stimulation.</AbstractText>
<AbstractText Label="METHODS" NlmCategory="METHODS">The study included 20 patients with faecal incontinence and a positive percutaneous nerve evaluation test: 19 women and one man, with a median age of 63 (range 28-78) years. Colorectal scintigraphy was performed to assess colorectal emptying at defaecation before and after implantation. Segmental colorectal transit times were determined using radio-opaque markers.</AbstractText>
<AbstractText Label="RESULTS" NlmCategory="RESULTS">The median frequency of defaecation per 3 weeks decreased from 56 (range 19-136) to 26 (range 12-78) (P < 0.002). At defaecation, antegrade transport from the ascending colon decreased from a median score of 8 (range 0-23) to 0 (range 0-11) per cent (P = 0.001), while retrograde transport from the descending colon increased from a median score of 0 (range 0-14) to 2 (range 0-30) per cent (P = 0.039). The median defaecation score was unchanged. There was a non-significant increase in median total gastrointestinal transit time from 2.5 (range 0.9-6.2) to 3.3 (range 0.8-6.2) days (P = 0.079).</AbstractText>
<AbstractText Label="CONCLUSION" NlmCategory="CONCLUSIONS">Sacral nerve stimulation reduces antegrade transport from the ascending colon and increases retrograde transport from the descending colon at defaecation. This may prolong colonic transit time and increase the storage capacity of the colon.</AbstractText>
<CopyrightInformation>2008 British Journal of Surgery Society Ltd. Published by John Wiley & Sons, Ltd.</CopyrightInformation>
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<LastName>Michelsen</LastName>
<ForeName>H B</ForeName>
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<Affiliation>Surgical Research Unit, Department of Surgery P, Aarhus University Hospital, Aarhus, Denmark. hbn@mail.tele.dk</Affiliation>
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<Country>England</Country>
<MedlineTA>Br J Surg</MedlineTA>
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<NameOfSubstance>Indium Radioisotopes</NameOfSubstance>
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<DescriptorName MajorTopicYN="N">Adult</DescriptorName>
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<DescriptorName MajorTopicYN="N">Aged</DescriptorName>
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<MeshHeading>
<DescriptorName MajorTopicYN="N">Defecation</DescriptorName>
<QualifierName MajorTopicYN="Y">physiology</QualifierName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N">Electric Stimulation Therapy</DescriptorName>
<QualifierName MajorTopicYN="Y">methods</QualifierName>
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<MeshHeading>
<DescriptorName MajorTopicYN="N">Fecal Incontinence</DescriptorName>
<QualifierName MajorTopicYN="N">physiopathology</QualifierName>
<QualifierName MajorTopicYN="N">radionuclide imaging</QualifierName>
<QualifierName MajorTopicYN="Y">surgery</QualifierName>
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<MeshHeading>
<DescriptorName MajorTopicYN="N">Female</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N">Gastrointestinal Transit</DescriptorName>
<QualifierName MajorTopicYN="Y">physiology</QualifierName>
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<DescriptorName MajorTopicYN="N">Humans</DescriptorName>
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<DescriptorName MajorTopicYN="N">Male</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N">Middle Aged</DescriptorName>
</MeshHeading>
<MeshHeading>
<DescriptorName MajorTopicYN="N">Sacrum</DescriptorName>
<QualifierName MajorTopicYN="Y">innervation</QualifierName>
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